The last five articles by the Brain Fuels (click on titles to read)
Intermittent fasting is popular today. One of the aspects of this calorie restriction techniques is periodic ketosis, which is proved to be neuroprotective. Another aspect is periodic interruption of glycolysis, which is also good for the brain. However, the Hellers were first to empirically formulate the idea and make it very dieter-friendly: Rachael F. Heller, Richard F. Heller. The Carbohydrate Addict’s Diet: The Lifelong Solution to Yo-Yo Dieting. Signet (1993)
<– Carbohydrate Addict Diet Food Pyramid
This diet is for you if you have:
• forceful hunger
• craving for carbohydrate-rich foods
• need for starches
• desire for snack foods, junk food, or sweets?
Do you have problems:
• staying away from food between meals
• staying away from snacks at night
• stopping a meal containing starches and sweets
• eating tasty food while not being hungry
• staying alert after a large meal
• staying alert early afternoon
• keeping your weight off after losing weight due to dieting
Do you tend to overeat these foods:
• Breads
• Bagels
• Cakes
• Cereal
• Chocolate
• Cookies
• Crackers
• fruit
• juice
• ice cream
• potatoes
• pasta
• rice
• popcorn
• sodas?
Do you indulge in:
• sugar substitutes
• alcohol
• monosodium glutamate?
If you answered “yes” to at least one of the questions in each category, the CAD might be right for you.
The diet prescribes two meals, called Complementary Meals, which limit carbohydrate generally same way most low carb diets do. Most people choose breakfast and lunch for their complementary meals. The diet allows one Reward Meal not limiting carbohydrate content but limiting this meal’s duration to strictly one hour. It is believed that with this meal planning you body is tricked into releasing less insulin. Thus, it better controls blood sugar levels and therefore stores less fat.
The diet starts with the Entry Plan. You eat two complementary meals and a reward meal, no snacks, for a week, then you weigh. Your plan for the next week will depend on your weight loss and your weight loss goal. For instance, if you loss was around 2 pounds, you go to the Plan A, which is essentially same plan, but you are allowed to have a low carb snack.
If after following the Entry Plan for a week you lost 0.5 lb. To 2 lb., you go to the Plan B, which is in fact staying on the Entry Plan for one more week.
If you didn’t lose any weight on Entry Plan, you go to the Plan C and this is an interesting part. All you do differently comparing with the Entry Plan, is eating two big salads made of leafy green vegetables before both of your two daily complementary meals.
There’s also the Plan D, for the most stubborn body weight, where you add one more salad, before your Reward Meal. This planning goes on every new week.
From the book:
Reprinted with permission
The ‘few foods’ elimination diet (Arch Dis Child, 2001 84:404–409) is considered “a valuable instrument” for both testing the foods to blame for ADHD and, after eliminating these foods, for improving children’s behavior. 69.4% reduction on the ADHD assessment scale comparing with 45.3% in control group without dietary intervention (Eur Child & Adolescent Psychiatry, Volume 18, Number 1 / January, 2009).
The method
There are so called oligo-antigenic foods — foods that are unlikely to produce an adverse behavioral response: lamb, chicken, potatoes, rice, banana, apple and brassica (e.g., broccoli, Brussels sprouts, cabbage, Chinese cabbage, cauliflower, kale, kohlrabi, etc).
Additional foods were reintroduced, one by one, and if there was no adverse reaction they were retained in the diet. Foods causing adverse reactions were tested in a double-blind control setting: out of two similar meals only one contained the food causing an adverse reaction another being an analog of different chemical nature, for example, cows milk versus soya milk.
The usual suspects
Cows milk caused an adverse reaction in 64% of children; chocolate (59%), grapes (49%), wheat (49%), oranges (45%), cows cheese (40%) and hens egg (39%).
Food intolerance and behavior
• Some children with ADHD respond adversely to certain foods.
• Among the more common foods to blame are wheat, dairy products and chocolate.
• Not all children sharing diagnosis such as ADHD responded similarly to the diet intervention.
There are quite a few so called “axes” where the brain is involved. The most studied is hypothalamic–pituitary–adrenal axis dealing mostly with stress and the sleep/wake cycle and the hypothalamic-pituitary-gonadal axis reproduction, life cycle, and sexual dimorphism & behavior. Recently, emerging evidence supports the existence of communication axes between other organs as well, with the central role of the brain remaining. The gut-brain-skin axis is thought to be responsible also for the stress challenge that, if not managed, can cause skin inflammation and the hair growth inhibition. The good news is, there are ways to deal with the challenge by improving of the microflora of the guts by probiotics (Exp Dermatol. 2010 Jan 25).
For example, myocardial infarction (heart attack) causes the release of pro-inflammatory substances that may affect the function of other organs including various structures brain where they result in an increase in cell death (J Psychopharmacol 2009, 23, 451–459; Biol Psychiatry 2006, 59, 430–433) while the friendly probiotic bacteria Lactobacillus helveticus and Bifidobacterium longum taken in combination reduced these adverse effects (British Journal of Nutrition (2009), 102:1420-1425).
A spectacular result proving the gut-brain axis influence on the quality of life has been presented in the European Journal of Clinical Nutrition (2007, 61, 355–361). Those participants of the double blind controlled trial who reported themselves to be constipated infrequently were more clearheaded, confident and elated. When the participants prone to be depressed at the onset of the trial where treated with probiotics, they responded by reporting themselves as happy rather than depressed while these changes were not observed in the control group taking milk drinks containing no probiotics.
Parkinson’s disease, though having some genetic forms, is thought to be largely life style-related and since no treatments exist to prevent or slow the disease down, environmental factors are of great interest to scientists. Earlier, in Germany (1) and Sweden, (2) consumption of coffee or caffeine have been shown to lower risk of Parkinson’s disease. However, there were some problems with interpretation of the results: coffee drinking was positively associated with smoking and alcohol consumption (3).
The Harvard School of Public Health followed up 183267 healthy people (free of Parkinson’s disease, cancer or stroke) during 10 years, watching their caffein intake with coffee, tee, chocolate and adjusting the results for age since and smocking since these two were strong risk factors in themselves (3). 288 cases of Parkinson’s disease were registered during this time. Women were more active coffee drinkers: the lower quintiles of caffein intake (taken as the reference point) in their population was 7 times higher than in men’s population.
Every other quintile in men had a lower risk of Parkinson’s disease, however, in women, the highest quintile was not associated with risk decrease – women consuming the largest amounts of caffein have had the same risk as those consuming the least caffein and for some of them the risk increased up to 1.8 times. The average highest caffein intake was 1.3 times higher in women than in men but the authors hesitate contributing the U-shaped of intake/risk curve to this difference and argued that “plausible biological basis for a protective effect of caffeine” should be established before making conclusions.
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Among those shared with me their weight loss results while on Atkins diet, 347 dieters reported effects beyond weight loss (or its absence):
Reported negative results:
Mood/energy
This particular effect is perhaps the most controversial because it is against the observations, including those conducted in controlled clinical settings, that carbohydrate-rich meals improve mood and energy levels. Apparently, the positive influence reported by the dieters, were due to Atkins diet long-term effects, because during first several days on the diet there were effects consistent with clinical observations on short-term effects of direct intra-gastric infusions of nutrients:
“Hedonic tone was greater and tension lower after the saline and sucrose infusions than after the lipid infusion. From 3 to 3.5 h after ingestion, subjects felt significantly more sleepy after the lipid infusion than they did at these times after the saline infusion, and significantly more dreamy after the lipid infusion than they did after the sucrose infusion. (Physiology & Behavior. 63(4):621-8, 1998)
Another article reporting the influence of nutrients on mood, stress that there were acute and not long term effects:
“Mood improved (a decline in fatigue/dysphoria) following the low-fat/high carb breakfast compared to medium-fat/ medium-carbohydrate or high-fat/low-carbohydrate meals.” (”Acute effects on mood and cognitive performance of breakfasts differing in fat and carbohydrate content. “Appetite. 27(2):151-64, 1996)
The short-term positive effects of high-carb meals can be used, for example, for alleviating the PMS syndrome:
“The experimental carbohydrate intervention significantly decreased self-reported depression, anger, confusion, and carbohydrate craving 90-180 minutes after intake. Memory word recognition was also improved significantly.” (Obstetrics & Gynecology. 86(4 Pt 1):520-8, 1995)
It is interesting that not all of the clinical studies came to the above conclusion. Study conducted by University of Sheffield, demonstrated that meals, particularly when rich in fat, significantly reduced pain perception in healthy human subjects.( Physiology & Behavior. 65(4-5):643-8, 1999)
Carbohydrate craving obese patients do not improve their mood states through ingestion of a carbohydrate-rich snack. (International Journal of Obesity & Related Metabolic Disorders. 21(10):860-4, 1997)
There were no differences in mood between the groups receiving high-carb drink or water during performance of the military tasks. (Aviation Space & Environmental Medicine. 68(5):384-91, 1997)
The ingestion of sucrose failed to have any substantial effect on mood (Physiology & Behavior. 58(3):421-7, 1995)
“The carbohydrate-supplemented group had a greater total energy intake and carbohydrate intake. No significant differences between carbohydrate were observed in remaining psychological, physiological, or performance-related variables.” (International Journal of Sport Nutrition. 5(2):125-35, 1995)
These are rather typical messages:
In 1989-99, an association was found, between dietary fat composition and cognitive performance in later adult years: the higher intake of monounsaturated and polyunsaturated fats and the lower intake of saturated fat — the higher cognitive performance. Another, epidemiologic study conducted in 1997 suggested that high intake of total fat, saturated fat, and dietary cholesterol may increase the risk of dementia.
However, researchers at St Luke’s Medical Center, Chicago, Ill found increased risk of Alzheimer’s disease among people with high intakes of saturated and trans-unsaturated fats and decreased risk with high intakes of polyunsaturated and monounsaturated fats. Consumption of vegetable fat and a high ratio of polyunsaturated to saturated fats were also protective, whereas total fat, animal fat, and dietary cholesterol had no association with Alzheimer disease.
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